Todd L. Sack, M.D., F.A.C.P.

Scientific Publications

Papers
      Hwang WI, Sack TL, Kim YS.  “Effects of cyclic-adenosine 3’ :5’- monophosphate upon glycoprotein and carcinoembryonic antigen synthesis and release by human colon cancer cells.”  Cancer Research 1986; 46: 3371-3374
Sack TL, Gum J, Kim YS.  “Cyclic-AMP-stimulated synthesis and release of carcinembryonic antigen by pancreatic cancer cells.”  International Journal of Pancreatology, 1988; 3: 171-184
Sack TL, Gum JR, Low M, Kim YS.  “Release of carcinoembryonic antigen from human colon cancer cells by phosphatidylinositol – specific phyospholipase C.” Journal of Clinical Investigation, 1988: 82: 586-593
Toribara N, Sack TL, Gum JR, Ho SB, Shively JE, Wilson JKV, KimYS. “Heterogeneity in the induction and expression of carcinoembryonic antigen-related antigens in human colon caner cell lines.”  Cancer Research”, 1989; 49: 3321-3327
Gum GR, Hicks JW, Sack TL, Kim YS.  “Molecular cloning of complementary cDNA’s encoding alkaline phosphatase in human colon cancer cells.” Cancer Research 1990; 50: 1085-1091
Sack TL.  “The medical acute abdomen: a diagnostic guide.” Jacksonville Medicine  1993:  44:65-67
Sack TL.  “ The new hepatitis alphabet: A through E”.  Jacksonville Medicine 1993; 44: 167-169
Reviews and Chapters
Bresalier RS, Borland CR, Sack TL, Kim YS.  “Cancer of the gastrointestinal tract.” In Kern F Jr., Blum AL (Eds): The Gastroenterology Annual, 3. New York: Elsevier, 1986: 413-469
Sack TL, Kim YS.  “Pancreatic cancer-associated carbonhydrate antigens.”  In Delmont J. (Ed): Cancer of the Exocrine Pancreas.  Basel: Karger, 1986: 48-59
Sack TL, Sleisenger MS.  “Effects of systemic and extraintestinal disease upon the gut.” In Sleisenger MS, Fordtran JH (Eds): Gastrointestinal Disease: Pathophysiology, Diagnosis, and Management, (4th Edition). Philadelphia: Saunders, 1988: 488-528
Sack TL, Silverman S. Jr., “Oral disease and cutaneous manifestations of gastrointestinal disease.” In Sleisenger MS, Fordtran JH (Eds):  Gastrointestinal Disease:  Patholphysiology, Diagnosis and Management, (4th Edition). Philadelphia; Saunders, 1988: 529-538
Abstracts and Presentations
Sack TL, Hicks J, Kim YS. “Cyclic-AMP increases the release and content of carcinoembryonic antigen from human pancreatic cancer cells in vitro.  “Gastroenterology 1985; 88: 1566.  Oral presentation at the AGA Annual Meeting, May, 1985
Sack TL, Hwang WI, Kim YS. “Cyclic-AMP increases the synthesis and release of glycoproteins and carcinoembryonic antigen by human colonic cancer cells.” Clinical Research 1986; 34: 36A
Sack TL, Gum JR, Kim YS. “Carcinoembryonic antigen release by colon cancer cells: role of phosphatidylinositol – specific phospholipase C.” Gastroenterology 1977: 92: 1608. Oral presentation at the AGA Annual Meeting, Mary 1987
Sack TL. “Porphyrin excretion and hepatic porphyrin content in hepatoma-associated porphyria.”  Hepatology 1987; 7: 1098
Sack TL, Gum JR, Kim YS. “Carcinoembryonic antigen and placental – like alkaline phosphatase release by human colon caner cells: presence of covalently-bound lipid and release by exogenous or endogenous phosphatidylinositol – specific phospholipase C.” Gastroenterology 1988: 94: A393. Oral presentation at the AGA Annual Meeting, May 1988
Toribara NW, Sack TL, Gum JR, Kim YS. “Effects of sodium butyrate on expression of carcinoembryonic antigen (CEA) family genes by human neoplastic colon cells.” Gastroenterology, 1988: 94: A646

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