Peter Grubel, M.D.

Scientific Publications

Published Papers
   
  Grübel P, Choi Y, Knox T, Schneider D, Zinny M, Cave DR. Severe isolated Crohn’s like disease of the gastroduodenal tract. Dig Dis Sci 2003; 48(7):1360-1365
  Grübel P, El-Helw T, Pratt DS. Transjugular intrahepatic portosystemic shunt (TIPS) for portal decompression prior to abdominal and retroperitoneal surgery in patients with severe portal hypertension. J Clin Gastro 2002; 34:489-490
  Argyros FC, Gosh M, Cave DR, Grübel P. Evaluation of DNA extraction and new primer based on the isocitrate dehydrogenase gene for detection of Helicobacter pylori in feces. J Clin Microbiol 2000; 10:3755-3758
      Grübel P, Huang L, Masubuchi N, Stutzenberger FJ, Cave DR. Detection of Helicobacter pylori DNA in houseflies (Musca domestica) on three continents. Lancet 1998; 352:788-789
  Grübel P, Cave DR. Factors affecting solubility and penetration of clarithromycin through gastric mucus. Aliment Pharm Therap 1998; 6:569-576
Grübel P, Cave DR. Sanitation and houseflies: factors for the transmission of Helicobacter pylori – a minireview. Bull Inst Pasteur 1998; 2:83-91
Grübel P. Les mouches, un vecteur de Helicobacter pylori. Journal Suisse de Pharmacie1997; 16:424-425.
Grübel P, Hoffman JS, Chong FK, Burstein NA, Sheff BR, Mepani C, Cave DR. Vector potential of houseflies (Musca domestica) for Helicobacter pylori. J Clin Microbiol 1997; 6:1300-1303
Grübel P, Bhaskar KR, Cave DR, Garik P, Stanley HE, LaMont JT. Interaction of an aluminum-magnesium containing antacid and gastric mucin: possible contribution to the cytoprotective mechanism of antacid. Aliment Pharm Therap 1997; 1:139-145
Grübel P, Cave D.R. Flies - carriers and vectors of transmission of Helicobacter pylori. Fortschr.Med 1997; 3:35-36
Miederer SE, Grübel P. Profound increase of Helicobacter pylori urease activity in gastric antral mucosa at low pH. Dig Dis Sci 1996; 41:944-949
Miederer SE, Grübel P. Optimale oder maximale Säurehemmung in der Ulkustherapie? Eine Entscheidungshilfe für die tägliche Praxis anhand eigener Untersuchungen. Fortschr Med 1994; 16:235-239
 
Books and Chapters
Grübel P, Cave DR. Ischemic colitis. In: Colonic diseases. Editor: Koch TR. Humana Press Inc, Totowa NJ, USA 2003
Cave DR, Grübel P, Huang L. Vectors for transmission. In: Helicobacter pylori: Basic mechanisms to clinical cure 1998. Editors: Hunt RH; Tytgat GNJ, Kluwer Academic Publishers, USA 1998; Chapter 9:68-74
Miederer SE, Grübel P. Optimale oder maximale Säurehemmung: Was ist besser in der Ulkustherapie? In: Ulcus pepticum und Diabetes mellitus. Editor: Dammann HG, Editio medica, Hamburg, Germany 1994; 13-21.
 
Electronic References
Grübel P, LaMont JT. Colonic ischemia. UptoDate Inc., Wellesley MA, USA 2008
 
Abstracts
Grübel P. EUS guided electrocautery therapy for refractory anastomotic stricture of the esophagus. Presented at the 16th International Symposium on Endoscopic Ultrasonography. San Francisco CA, September 2008. In press
Grübel P, Choi Y, Knox T, Schneider D, Zinny M, Cave DR. Severe isolated Crohn’s like disease of the gastroduodenal tract in four patients. Am J Gastro 2001; 9:644 (Presented at the 66th American College of Gastroenterology meeting. Las Vegas NA, October 2001)
Grübel P, El-Helw T, Pratt DS. TIPS for portal decompression to allow colectomy and nephrectomy in two Child’s C cirrhotic patients with severe portal hypertension. Am J Gastro 2001; 9:645 (Presented at the 66th American College of Gastroenterology meeting. Las Vegas NA, October 2001)
Grübel P, Bhaskar KR, LaMont JT. Heparin causes profound increase of gastric mucus viscosity at low pH. Gastroenterology 2000; 4:1395 (Presented at the 102th Digestive Disease Week. San Diego, CA. May 2000)
Grübel P, Frenck RW, Willis DH, Goddard PJ, Abu-Elyazeed RR, Naficy A, Cave DR. HpSA enzyme immunoassay for detection of H. pylori from stool samples collected from a field setting in Egypt. Gastroenterology 1999; 4:G0772
Argyros FC, Gosh M, Grübel P, Cave DR. Comparison of DNA-extraction methods used to detect Helicobacter pylori in feces. Gastroenterology 1999; 4:G0492 (Presented at the 101th Digestive Disease Week. Orlando FL, May 1999)
Grübel P, Huang L, Masubuchi N, Stutzenberger FJ, Goddard PJ, Hoffman JS, Takahashi S, Cave DR. Helicobacter pylori in wild American and European houseflies (Musca domestica). Gastroenterology 1998; 4:G0575 (Presented as talk at the 100th Digestive Disease Week. New Orleans LO, May 1998)
Huang L, Grübel P, Masubuchi N, Goddard PJ, Hoffman JS, Cave DR. Detection of Helicobacter pylori in contaminated samples using polymerase chain reaction based on the isocitrate dehydrogenase gene. Gastroenterology 1998; 4:G0634 (Presented as talk at the Helicobacter pylori: Basic mechanisms to clinical cure meeting. San Diego CA, January 1998)
Grübel P, Cave DR. Effect of topically active antiulcer preparations on penetration of clarithromycin through gastric mucus 1998; ICMAS (Presented at the 4th International conference on the macrolides, azalides, streptogramins & ketolides. Barcelona, Spain, January 1998)
Grübel P, Hoffman JS, Chong FK, Burstein NA, Sheff BR, Mepani C, Cave DR. Houseflies (Musca domestica): novel suspects for the transmission of Helicobacter pylori. Gastroenterology 1997; 4:A134 (Presented at the 99th Digestive Disease Week. Washington DC, May 1997)
Grübel P, Cave DR Penetration of amoxicillin and clarithromycin through gastric mucus is affected by the aluminum-magnesium containing antacid Riopan. Gastroenterology 1997; 4:A135 (Presented at the 99th Digestive Disease Week. Washington DC, May 1997)
Grübel P, Cave DR. Penetration of amoxicillin, clarithromycin and tetracycline through gastric mucus. Am J Gastro 1996; 91(9):650 (Presented at the 61st American College of Gastroenterology meeting. Seattle WA, October 1996)
Grübel P, Hoffman JS, Chong FK, Burstein NA, Sheff BR, Mepani C, Cave DR. Vector potential of houseflies (Musca domestica) for Helicobacter pylori. Gut 1996; 2:A88 (Presented as talk at the IXth International Workshop on gastroduodenal Pathology and Helicobacter pylori, Copenhagen, Denmark, October 1996)
Grübel P, Cave DR. Effect of the aluminum-magnesium containing antacid Riopan on the penetration of amoxicillin and clarithromycin through gastric mucus. Gut 1996; 2:A11 (Presented at the IXth International Workshop on gastroduodenal Pathology and Helicobacter pylori, Copenhagen, Denmark, October 1996)
Grübel P, Cave DR. Effect of drug formulation of clarithromycin on its solubility, gastric mucus viscosity, and mucus permeability. Gastroenterology 1996; 4:A125 (Presented at the 97th Digestive Disease Week. San Francisco CA, May 1995)
Miederer SE, Grübel P Profound increase of Helicobacter pylori urease activity in gastric antral mucosa at low pH. Gut 1995; 37(suppl 1):A83 (Presented at the VIIIth International Workshop on gastroduodenal Pathology and Helicobacter pylori, Edinburgh, Scotland, July 1995)
Grübel P, Bhaskar KR, Garik P, Stanley HE, LaMont JT Interaction of hydrotalcit and gastric mucin and its possible role in the protective function of the antacid. Gastroenterology 1995; 4:A105 (Presented as talk at the 96th Digestive Disease Week. San Diego CA, May 1995)
Castagliuolo I, Lucas WB, LaMont JT, Leeman S, Baker C, Grübel P, Nikkulasson Z, Carraway RE, Pothoulakis C. Stress activates rat colonic mucin release via neuronal pathways and release of neurotensin (NT) and prostaglandine E2 (PGE2). Gastroenterology 1995; 4:A176 (Presented as talk at the 96th Digestive Disease Week. San Diego CA, May 1995)
Miederer SE, Grübel P. Effect of Type B- (Helicobacter pylori) gastritis on serum gastrin regulation in subjects with achlorhydria. Gastroenterology 1994; 4:A139 (Presented at the 95th Digestive Disease Week. New Orleans, LO, May 1994)
Miederer SE, Grübel P. Influence of pH on ammonia (NH3) formation by Helicobacter pylori. Gastroenterology 1994; 4:A139 (Presented at the 3rd European Gastroenterology Week. Oslo, Norway, June 1994)
Reimer P, Milbradt H, Kant C, Grübel P, Sturm J. Sonography of the postoperative shoulder: diagnostic approach to the postoperative shoulder. Radiology 1989; 11 (A) (Presented at the 75th RSNA meeting. Chicago IL, November 1989)
 
Abstracts Presented At Symposia
Presented as poster at the 16th International Symposium on Endoscopic Ultrasonography. San Francisco CA, September 2008.
Presented as poster at the 66th American College of Gastroenterology meeting. Las Vegas NA, 2001.
Presented as poster at the 66th American College of Gastroenterology meeting. Las Vegas NA, 2001.
Presented as poster at the 102th Digestive Disease Week. San Diego, CA. May 2000.
Presented as poster at the 101th Digestive Disease Week. Orlando, FL. May 1999.
Presented as poster at the 101th Digestive Disease Week. Orlando, FL May 1999.
Presented as talk at the 100th Digestive Disease Week. New Orleans, LA, May 1998.
Presented as talk at the Heliobacter pylori. Basic mechanisms to clinical cure meeting. San Diego CA, January 1998
Presented as poster at the 4th International conference on the macrolides, azalides, streptogramins & ketolides. Barcelona, Spain, January 1998.
Presented as poster at the 99th Digestive Disease Week. Washington DC, May 1997
Presented as poster at the 99th Digestive Disease Week. Washington DC, May 1997
Presented as poster at the 61st American College of Gastroenterology meeting. Seattle WA, October 1996
Presented as talk at the IXth International Workshop on gastroduodenal Pathology and Heliobacter pylori, Copenhagen, Denmark, October 1996
Presented as poster at the IXth International Workshop on, Copenhagen, Denmark, October 1996
Presented as poster at the 97th Digestive Disease Week. San Francisco CA, May 1995
Presented as poster at the VIIIth International Workshop on gastroduodenal Pathology and Heliobacter pylori, Edinburgh, Scottland, July 1995
Presented as talk at the 96th Digestive Disease Week. San Diego CA, May 1995
Presented as poster at the 95th Digestive Disease Week. New Orleans LA, May 1994
Presented as poster at the 3rd European Gastroenterology Week. Oslo, Norway, June 1994
Presented as poster at the 75th RSNA meeting. Chicago IL, November 1989
 
Invited Talks and Interviews
Colon cancer screening. 1st annual advances in comprehensive oncology care, Florida Hospital, Daytona Beach, FL, June 2008.
Endoscopic ultrasound. Grand Rounds, Halifax Medical Center, Daytona Beach, FL November 2007
Ischemic colitis. Research seminar, New England Medical Center, Boston MA, February 2001
Epidemiology and transmission of Heliobacter pylori. German Gastroenterology Association Congress, Bielefeld, Germany, May 2000
Update on epidemiology on Heliobacter pylori. Research seminar, New England Medical Center, Boston MA, April 2000
Physical properties of mucus and clinical implications. Research seminar, New England Medical Center, Boston MA, November 1999
Factors affecting gastric mucus barrier properties and clinical implications. Research seminar GelTex Inc., Waltham MA, September 1999
The gastric mucus barrier and its interaction with antacids and antibiotics. Seminars in Gastroenterology, University of Ulm, Germany, March 1996
Pharmacokinetics of antacids and antibiotics in the gastric mucus layer. Byk Gulden Research Seminar. Konstanz, Germany, June 1995
Antacids and polymers affect the gastric mucus barrier. Current Research at Tufts University School of Medicine. Cape Cod, MA, USA, April 1995.
The interaction of antacids with gastric mucus. Congress: Stomach management in gastroenterological clinics. Bonn, Germany, August 1994
 
On Heliobacter pylori
Public broadcasting TV station [PBS], USA. Scientific documentation on the discovery and history of H.Pylori, broadcasted worldwide as scientific TV documentation in 99/00.
CNN headline news, USA, 8-97
TV Channel 4 (NBC) prime news, Boston, 8-97
Discovery Channel, USA-Canada, 8-97
BBC World Services, science in action, UK, 7-97
Public Broadcasting Station, USA, 6-97
TV Channel 5 Boston, New England, TV-prime news, 12-96
RTL- Explosiv, European TV- prime news, 12-96
WBZ Boston (CBS), TV- prime news, 11-96
Newsweek, USA, 7-97; Business Week, USA, 6-97; The New York Times, USA, 7-97; Science News, USA 7-97; PR World Health Network, UK, 7-97; Boston Globe, USA; 7-97